A comprehensive family history centered on the Nixon family and particularly the descendants of Andrew Jackson Nixon and Lurana Wootten. The volume traces the family name and its early forms, discusses Nixon families in Britain, Ireland, and America, and then presents detailed chapters on successive generations of the family. The chapter structure includes Frances Marion Nixon and Catherine Elliott; Andrew Jackson Nixon and Lurana Wootten; James G. Nixon and Mary Hatfield; Andrew Jackson Nixon II and Louise Strackbein; William Jasper Nixon and Emily Dickson; and additional Nixon family branches.

The book was assembled from extensive family research and contributions. Its introductory history explains that Clayton Nixon spent years collecting family data and that, after his death, a committee worked to bring the material together and update it. The resulting volume preserves genealogical information, family photographs, historical accounts, family stories, and records concerning numerous descendants and branches of the family.